{"id":12161,"date":"2015-03-09T11:57:09","date_gmt":"2015-03-09T10:57:09","guid":{"rendered":"http:\/\/www.emiliosilveravazquez.com\/blog\/?p=12161"},"modified":"2015-03-09T11:57:09","modified_gmt":"2015-03-09T10:57:09","slug":"nasa-ames-reproduces-the-building-of-life-in-laboratory","status":"publish","type":"post","link":"http:\/\/www.emiliosilveravazquez.com\/blog\/2015\/03\/09\/nasa-ames-reproduces-the-building-of-life-in-laboratory\/","title":{"rendered":"NASA Ames Reproduces the Building of Life in Laboratory"},"content":{"rendered":"<div style=\"text-align: justify;\"><strong><strong>Nuestro contertulio<\/strong><\/strong><strong> jccazorla39, me env\u00eda un correo que est5ima de inter\u00e9s para que todos lo podamos leer, y, habi\u00e9ndolo hecho, resulta que he decidido pasarlo para todos. La fuente es la propia NASA.<\/strong><br \/>\n<strong><strong><\/strong><\/strong><\/div>\n<div id=\"feature-content\">\n<div>\n<div>\n<div>\n<div>\n<div style=\"text-align: justify;\">\n<div>\n<div>\n<div>\n<div>\n<div><a href=\"http:\/\/www.nasa.gov\/sites\/default\/files\/thumbnails\/image\/acd15-0032-001_2_0.jpg\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/www.nasa.gov\/sites\/default\/files\/styles\/673xvariable_height\/public\/thumbnails\/image\/acd15-0032-001_2_0.jpg?itok=8r2ANzVn\" alt=\"Scientists simulate space in Ames Astrochemistry Lab\" width=\"673\" height=\"484\" \/><\/a><\/div>\n<\/div>\n<\/div>\n<div>\n<div>\n<div>Left to right: Ames scientists Michel Nuevo, Christopher Materese and Scott Sandford reproduce uracil, cytosine, and thymine, three key components of our hereditary material, in the laboratory.<\/div>\n<\/div>\n<\/div>\n<div>\n<div>Image Credit:<\/div>\n<div>\n<div>NASA\/ Dominic Hart<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p style=\"text-align: justify;\">NASA scientists studying the origin of life have reproduced uracil, cytosine, and thymine, three key components of our hereditary material, in the laboratory. \u00a0They discovered that an ice sample containing pyrimidine exposed to ultraviolet radiation under space-like conditions produces these essential ingredients of life.<\/p>\n<p style=\"text-align: justify;\">Pyrimidine is a ring-shaped molecule made up of carbon and nitrogen and is the central structure for uracil, cytosine, and thymine, which are all three part of a genetic code found in ribonucleic (RNA) and deoxyribonucleic acids (DNA). RNA and DNA are central to protein synthesis, but also have many other roles.<\/p>\n<div style=\"text-align: justify;\">\n<div>\n<div>\n<div>\n<div><a href=\"http:\/\/www.nasa.gov\/sites\/default\/files\/thumbnails\/image\/acd15-0032-002_2.jpg\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/www.nasa.gov\/sites\/default\/files\/styles\/226xvariable_height\/public\/thumbnails\/image\/acd15-0032-002_2.jpg?itok=h885u5To\" alt=\"Ames Astrochemistry Lab UV lamp\" width=\"226\" height=\"170\" \/><\/a><\/div>\n<\/div>\n<div>\n<div>\n<div>An ice sample is held at approximately -440 degrees Fahrenheit in a vacuum chamber, where it is irradiated with high energy UV photons from a hydrogen lamp. The bombarding photons break chemical bonds in the ice samples and result in the formation of new compounds, such as uracil.<\/div>\n<\/div>\n<\/div>\n<div>\n<div>Image Credit:<\/div>\n<div>\n<div>NASA\/Dominic Hart<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p style=\"text-align: justify;\">&#8220;We have demonstrated for the first time that we can make uracil, cytosine, and thymine, all three components of RNA and DNA, non-biologically in a laboratory under conditions found in space,&#8221; said Michel Nuevo, research scientist at NASA&#8217;s Ames Research Center, Moffett Field, California. \u00a0&#8220;We are showing that these laboratory processes, which simulate conditions in outer space, can make several fundamental building blocks used by living organisms on Earth.&#8221;<\/p>\n<p style=\"text-align: justify;\">An ice sample is deposited on a cold (approximately \u2013440 degrees Fahrenheit) substrate in a chamber, where it is irradiated with high-energy ultraviolet (UV) photons from a hydrogen lamp. \u00a0The bombarding photons break chemical bonds in the ices and break down the ice&#8217;s molecules into fragments that then recombine to form new compounds, such as uracil, cytosine, and thymine.<\/p>\n<p style=\"text-align: justify;\">NASA Ames scientists have been simulating the environments found in interstellar space and the outer Solar System for years. \u00a0During this time, they have studied a class of carbon-rich compounds, called polycyclic aromatic hydrocarbons (PAHs), that have been identified in meteorites, and which are the most common carbon-rich compound observed in the universe. \u00a0PAHs typically are structures based on several six-carbon rings that resemble fused hexagons, or a piece of chicken wire.<\/p>\n<p style=\"text-align: justify;\">The molecule pyrimidine is found in meteorites, although scientists still do not know its origin. \u00a0It may be similar to the carbon-rich PAHs, in that it may be produced in the final outbursts of dying, giant red stars, or formed in dense clouds of interstellar gas and dust.<\/p>\n<p style=\"text-align: justify;\">&#8220;Molecules like pyrimidine have nitrogen atoms in their ring structures, which makes them somewhat wimpy. \u00a0As a less stable molecule, it is more susceptible to destruction by radiation, compared to its counterparts that don&#8217;t have nitrogen,&#8221; said Scott Sandford, a space science researcher at Ames. \u00a0&#8220;We wanted to test whether pyrimidine can survive in space, and whether it can undergo reactions that turn it into more complicated organic species, such as the nucleobases uracil, cytosine, and thymine.&#8221;<\/p>\n<div style=\"text-align: justify;\">\n<div>\n<div>\n<div>\n<div><a href=\"http:\/\/www.nasa.gov\/sites\/default\/files\/thumbnails\/image\/nucleobases_pyrimidine_uracil_image.jpg\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/www.nasa.gov\/sites\/default\/files\/styles\/226xvariable_height\/public\/thumbnails\/image\/nucleobases_pyrimidine_uracil_image.jpg?itok=uCiWUopd\" alt=\"Nucleobases structures\" width=\"226\" height=\"165\" \/><\/a><\/div>\n<\/div>\n<div>\n<div>\n<div>Pyrimidine is a ring-shaped molecule made up of carbon and nitrogen and is the central structure for uracil, cytosine, and thymine, which are found in RNA and DNA.<\/div>\n<\/div>\n<\/div>\n<div>\n<div>Image Credit:<\/div>\n<div>\n<div>NASA<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div style=\"text-align: justify;\">\n<div>\n<div>\n<div>\n<div>\n<div><a href=\"http:\/\/www.nasa.gov\/sites\/default\/files\/thumbnails\/image\/nucleobases_cytosine_thymine_image.jpg\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/www.nasa.gov\/sites\/default\/files\/styles\/226xvariable_height\/public\/thumbnails\/image\/nucleobases_cytosine_thymine_image.jpg?itok=aUTJO6E2\" alt=\"Nucleobases cytosine thymine image\" width=\"226\" height=\"167\" \/><\/a><\/div>\n<\/div>\n<\/div>\n<div>\n<div>\n<div>The ring-shaped molecule pyrimidine is found in cytosine and thymine.<\/div>\n<\/div>\n<\/div>\n<div>\n<div>Image Credit:<\/div>\n<div>\n<div>NASA<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p style=\"text-align: justify;\">In theory, the researchers thought that if molecules of pyrimidine could survive long enough to migrate into interstellar dust clouds, they might be able to shield themselves from destructive radiation. \u00a0Once in the clouds, most molecules freeze onto dust grains (much like moisture in your breath condenses on a cold window during winter).<\/p>\n<p style=\"text-align: justify;\">These clouds are dense enough to screen out much of the surrounding outside radiation of space, thereby providing some protection to the molecules inside the clouds.<\/p>\n<p style=\"text-align: justify;\">Scientists tested their hypotheses in the Ames Astrochemistry Laboratory. \u00a0During their experiment, they exposed the ice sample containing pyrimidine to ultraviolet radiation under space-like conditions, including a very high vacuum, extremely low temperatures (approximately \u2013440 degrees Fahrenheit), and harsh radiation.<\/p>\n<p style=\"text-align: justify;\">They found that when pyrimidine is frozen in ice mostly consisting of water, but also ammonia, methanol, or methane, it is much less vulnerable to destruction by radiation than it would be if it were in the gas phase in open space. \u00a0Instead of being destroyed, many of the molecules took on new forms, such as the RNA\/DNA components uracil, cytosine, and thymine, which are found in the genetic make-up of all living organisms on Earth.<\/p>\n<p style=\"text-align: justify;\">&#8220;We are trying to address the mechanisms in space that are forming these molecules. \u00a0Considering what we produced in the laboratory, the chemistry of ice exposed to ultraviolet radiation may be an important linking step between what goes on in space and what fell to Earth early in its development,&#8221; said Christopher Materese, another researcher at NASA Ames who has been working on these experiments.<\/p>\n<p style=\"text-align: justify;\">&#8220;Nobody really understands how life got started on Earth. Our experiments suggest that once the Earth formed, many of the building blocks of life were likely present from the beginning. \u00a0Since we are simulating universal astrophysical conditions, the same is likely wherever planets are formed,&#8221; says Sandford.<\/p>\n<p style=\"text-align: justify;\">Additional team members who helped perform some of the research are Jason Dworkin, Jamie Elsila, and Stefanie Milam, three NASA scientists at NASA&#8217;s Goddard Space Flight Center in Greenbelt, Maryland.<\/p>\n<p style=\"text-align: justify;\">The research was funded by the NASA Astrobiology Institute (NAI) and the NASA Origins of Solar Systems Program. \u00a0The NAI is a virtual, distributed organization of competitively-selected teams that integrates and funds astrobiology research and training programs in concert with the national and international science communities.<\/p>\n<p style=\"text-align: justify;\">Ruth Marlaire<br \/>\nAmes Research Center, Moffett Field, Calif.<br \/>\n650-604-4789<br \/>\n<a href=\"mailto:jessica.culler@nasa.gov\">ruth.marlaire@nasa.gov<\/a><\/p>\n<p style=\"text-align: justify;\"><em>To receive local-only NASA Ames news, email <a href=\"mailto:local-reporters-request@lists.arc.nasa.gov\">local-reporters-request@lists.arc.nasa.gov<\/a> with &#8220;subscribe&#8221; in the subject line. 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La fuente es la propia NASA. Left to right: Ames scientists Michel Nuevo, Christopher Materese and Scott Sandford reproduce uracil, cytosine, and thymine, three key components of our [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_s2mail":"yes","footnotes":""},"categories":[142],"tags":[],"_links":{"self":[{"href":"http:\/\/www.emiliosilveravazquez.com\/blog\/wp-json\/wp\/v2\/posts\/12161"}],"collection":[{"href":"http:\/\/www.emiliosilveravazquez.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.emiliosilveravazquez.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.emiliosilveravazquez.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.emiliosilveravazquez.com\/blog\/wp-json\/wp\/v2\/comments?post=12161"}],"version-history":[{"count":0,"href":"http:\/\/www.emiliosilveravazquez.com\/blog\/wp-json\/wp\/v2\/posts\/12161\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.emiliosilveravazquez.com\/blog\/wp-json\/wp\/v2\/media?parent=12161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.emiliosilveravazquez.com\/blog\/wp-json\/wp\/v2\/categories?post=12161"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.emiliosilveravazquez.com\/blog\/wp-json\/wp\/v2\/tags?post=12161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}